Thursday, March 8, 2012

Light triggers eyeless hydra to sting prey - George Foulsham - Futurity.org



Thanks to Mike OHare for the link.





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"Hydra stinging cells were already known to be touch sensitive and taste sensitive, but no one had ever thought before to look for light sensitivity—probably because they don’t have eyes," says Todd Oakley. "We're the first to have found that. And we found not only that light-sensitivity genes are expressed near hydra stinging cells, but that under different light conditions, these cells have different propensities to be fired." (Credit: David Plachetzki)


Hydra, a freshwater polyp—along with jellyfish, sea anemones, and corals in the Cnidaria family—use stinging cells, or cnidocytes, to catch prey. Hydra tentacles contain barbed, poison-containing cnidocytes that they use to stun animals, such as water fleas and plankton, before eating them alive. They’re also used for self-defense and locomotion.


New research reported in the journal BMC Biology, reveals that light, or the lack thereof, has a direct effect on hydras’ propensity to fire their stinging cells—a discovery that “tells us something completely new about the biology of these animals, and we think this could extend to other cnidarians,” says Todd Oakley, professor of ecology, evolution, and marine biology at the University of California, Santa Barbara.


“Hydra stinging cells were already known to be touch sensitive and taste sensitive, but no one had ever thought before to look for light sensitivity—probably because they don’t have eyes,” he says. “We’re the first to have found that. And we found not only that light-sensitivity genes are expressed near hydra stinging cells, but that under different light conditions, these cells have different propensities to be fired.”


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Making memories: How one protein does it - - - MedicalXpress



A neuron (red) accumulates messages (green) when treated with BDNF. Credit: Johns Hopkins Medicine


Studying tiny bits of genetic material that control protein formation in the brain, Johns Hopkins scientists say they have new clues to how memories are made and how drugs might someday be used to stop disruptions in the process that lead to mental illness and brain wasting diseases.


In a report published in the March 2 issue of Cell, the researchers said certain microRNAs—genetic elements that control which proteins get made in cells— are the key to controlling the actions of so-called brain-derived neurotrophic factor (BDNF), long linked to brain cell survival, normal learning and memory boosting.


During the learning process, cells in the brain's hippocampus release BDNF, a growth-factor protein that ramps up production of other proteins involved in establishing memories. Yet, by mechanisms that were never understood, BDNF is known to increase production of less than 4 percent of the different proteins in a brain cell.


That led Mollie Meffert, M.D., Ph.D., associate professor of biological chemistry and neuroscience at the Johns Hopkins University School of Medicine to track down how BDNF specifically determines which proteins to turn on, and to uncover the role of regulatory microRNAs.


MicroRNAs are small molecules that bind to and block messages that act as protein blueprints from being translated into proteins. Many microRNAs in a cell shut down protein production, and, conversely, the loss of certain microRNAs can cause higher production of specific proteins.
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Antimatter ‘measured’ for the first time, could reveal building blocks of the universe - Joseph Brean - National Post

Thanks to rod-the-farmer for the link.


Scientists related to Canadian institutions involved with the ALPHA antimater project are gathered by a superconducting magnet. The more obvious vertical cylinder to on the right is a container for liquid helium (a 'dewar').

Canadian-led team at the European nuclear research agency has succeeded in trapping particles of anti-matter long enough to measure how they react to increasing energy, in a groundbreaking experiment that heralds a new age of empirical research on the most bizarre stuff in existence.

“We’re going down a path of trying to study a fiendishly difficult atom, to begin with, and we’ve got to be able to convince the world that we’re really able to manipulate them and to do something that’s going to turn into a precision experiment,” said Mike Hayden, a Simon Fraser University physicist, and a senior author on the paper, out Wednesday in the British science journal Nature. Other Canadian authors are from the universities of Calgary, British Columbia and Victoria, York University, the Canadian Institute for Advanced Research, and TRIUMF, Canada’s national particle physics lab in Vancouver.

“This paper marks the transition; we’re saying we’ve done this, we’re ready to go to this next stage.”
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TAGGED: PHYSICS, SPACE



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Countless millions of taxpayers’ money spent on discrimination in schools - Terry Sanderson - secularism.org.uk

We often complain about the increasing amount of religion in schools, but it is not until you look at the job advertisements in papers like the Times Educational Supplement and the Church Times that you come to realise just how determined the churches are to use schools as recruiting grounds. The TES Jobs Supplement – which is much bigger than the TES itself – reveals the level of religious infiltration in state schools - funded by you and me.

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In last week's issue for instance, there were dozens of recruitment ads for Church of England and Catholic schools. One example was St Claire's Catholic Primary School in Coalville, Leicestershire. They need a headteacher and the ad reads: "Our Catholic faith is at the heart of our school. Everything we say and do reflects the Christian message and we are committed to living the Gospel values each and every day."

Croughton All Saints CE Primary School in Northamptonshire is also looking for a headteacher who will "work closely with the Rector and Diocese to ensure that the Christian is embedded throughout the school's activities."

Or what about St Hilda's CE Primary School in Firswood, Manchester that wants a headteacher who is "fired by the church's mission expressed in education, and want to advance the Kingdom of God through church and school working closely together."

St Joseph's & St Teresa's in Doncaster wants a headteacher with a "strong personal faith and a clear vision of Catholic Education". St Bartholomew's CE Primary in Binley,Coventry is looking for a leader "whose vision and professionalism is underpinned by a clear and demonstrable faith."

St Mary's Island CE Primary school asks applicants for the headteacher post to "provide a faith reference" to prove that they will uphold the "Christian leadership that are at the heart of our caring environment".

The St Francis Xavier joint Roman Catholic and CE School is looking for a headteacher, saying: "We live and breathe our values. Respect, dignity, faith and justice are at the heart of our school". Unfortunately, religious discrimination of the most despicable kind is also at the heart of their school as "all applicants must be committed and practising Catholics".

And so it goes on, dozens and dozens of them, all requiring applicants to be of a particular faith and to be able to prove it, presumably with an approving letter from their local priest.

The fact that there are so many such ads may indicate that they are having problems finding enough pious teachers to fill the posts. It also indicates that because the diocese has complete control of them, they are being used as indoctrination centres.

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TAGGED: CHILDREN, EDUCATION, FAITH SCHOOLS, RELIGION



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Publication of the gorilla genome opens window onto human evolution - - - wellcome trust

The sequence of the gorilla genome is published today, completing the set for the living great apes. The findings provide a unique perspective on our own origins and are an important resource for research into human evolution and biology, as well as gorilla biology and conservation.

While confirming that our closest relative is the chimpanzee, the research reveals that much of the human genome more closely resembles the gorilla than it does the chimpanzee genome. This is the first time scientists have been able to compare the genomes of all four living great apes: humans, chimpanzees, gorillas and orang-utans.

Dr Aylwyn Scally from the team at the Wellcome Trust Sanger Institute, who led the research, explains: "The gorilla genome is important because it sheds light on the time when our ancestors diverged from our closest evolutionary cousins. It also lets us explore the similarities and differences between our genes and those of the gorilla, the largest living primate.

"Using DNA from Kamilah, a female western lowland gorilla, we assembled a gorilla genome sequence and compared it with the genomes of the other great apes. We also sampled DNA sequences from other gorillas in order to explore genetic differences between gorilla species."

The team searched more than 11 000 genes in human, chimpanzee and gorilla for genetic changes important in evolution. Humans and chimpanzees are genetically closest to each other over most of the genome, but the team found many places where this is not the case. 15 per cent of the human genome is closer to the gorilla genome than it is to chimpanzee, and 15 per cent of the chimpanzee genome is closer to the gorilla than human.
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TAGGED: GENETICS



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Wednesday, March 7, 2012

Afghan clerics' guidelines 'a green light for Talibanisation' - Emma Graham-Harrison - The Guardian

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Afghan policewomen at work: guidelines released by the country's top clerics have been described as reminiscent of the Taliban era when women couldn't go out without a male guardian. Photograph: Jalil Rezayee/EPA

Women are subordinate to men, should not mix in work or education and must always have a male guardian when they travel, according to new guidelines from Afghanistan's top clerics which critics say are dangerously reminiscent of the Taliban era.

The edicts appeared in a statement that also encouraged insurgents to join peace talks, fuelling fears that efforts to negotiate an end to a decade of war, now gathering pace after years of false starts and dead ends, will come at a high cost to women.

"There is a link with what is happening all over the country with peace talks and the restrictions they want to put on women's rights," said Afghan MP Fawzia Koofi, who warned that the new rules were a "green light for Talibanisation".

The points agreed at a regular meeting of the Ulema Council of top clerics are not legally binding. But the statement detailing them was published by the president's office with no further comment, a move that has been taken as a tacit seal of approval.

"Ultimately, I don't see a way you can read it as not coming from (Hamid) Karzai," said Heather Barr, Afghanistan researcher at Human Rights Watch. "It's probably not an extreme position for the Ulema Council, but it's an extreme position for Karzai, and not compatible with the constitution, or Afghanistan's obligations under international law."

The clerics renounced the equality of men and women enshrined in the Afghan constitution, suggesting they consider the document that forms the basis of the Afghan state to be flawed from a religious perspective.

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TAGGED: HUMAN RIGHTS, ISLAM, LAW, RELIGION



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Rick Santorum’s Virginia Church and Opus Dei - Molly Redden - The New Republic

Rick Santorum’s Catholic faith is an obvious centerpiece of his campaign for the GOP presidential nomination, and it is rare for him to speak without referencing his religious beliefs. It is also rare, however, to hear him speak about his particular church, St. Catherine of Siena, which he and his family have belonged to for at least a decade. Even his 2005 manifesto on his personal faith and politics, It Takes a Family, did not mention the church. I was curious to learn more about it, so last Friday morning, I attended a 9 a.m. Mass there.

St. Catherine is a modern, low-slung brick building that sits in the affluent and hilly Washington suburb of Great Falls, Virginia. It is a notably conservative congregation—its neat grounds include a “garden for the unborn,” and the schedule offers a Latin Mass each Sunday featuring Gregorian chant sung by a professional choir.

The church claims 3,400 parishioners. Supreme Court Justice Antonin Scalia and his wife attend Mass there; at one time or another, so have Redskins quarterbacks, the head of the National Rifle Association, and former FBI director Louis Freeh. (Members of the Branch Davidians once blocked the parking lot with a protest targeted at Freeh after the Waco raid, someone familiar with St. Catherine told me.) The church also suffered brief notoriety eleven years ago when FBI agent Robert Hanssen—then a member of the congregation—was arrested for selling intelligence to Russia. Mostly, the church is home to families with school-aged children—“big families, seven-, eight- or nine-children families,” as one parishioner told me. (None of the half-a-dozen parishioners I interviewed would agree to be quoted by name, and the parish office declined interview requests.) Bishop Anton Justs of Jelgava, Latvia, who oversaw the creation of St. Catherine in 1981 as a reverend in Arlington, wrote in an email that its wealthy congregants are known for generosity. “The Catholic Church Community in Great Falls is very dedicated, intellectual and keeps strongly to Christian values … The people of the parish have been very generous in terms of contributions to the church and humanitarian aid abroad. It has been over 20 years since I left St. Catherine, but people write to me, and at Christmas time enclose a check.”
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TAGGED: US POLITICS



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Study Reveals How Protein Machinery Binds and Wraps DNA to Start Replication - Karen McNulty Walsh & Peter Genzer - www.bnl.gov

UPTON, NY — Before any cell — healthy or cancerous — can divide, it has to replicate its DNA. So scientists who want to know how normal cells work — and perhaps how to stop abnormal ones — are keen to understand this process. As a step toward that goal, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory and collaborators have deciphered molecular-level details of the complex choreography by which intricate cellular proteins recognize and bind to DNA to start the replication process. The study is published in the March 7, 2012, issue of the journal Structure.

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The DNA replication origin recognition complex (ORC) is a six-protein machine with a slightly twisted half-ring structure (yellow). ORC is proposed to wrap around and bend approximately 70 base pairs of double stranded DNA (red and blue). When a replication initiator Cdc6 (green) joins ORC, the partial ring is now complete and ready to load another protein onto the DNA. This last protein (not shown) is the enzyme that unwinds the double stranded DNA so each strand can be replicated.

“Every cell starts to replicate its genome at defined DNA sites called ‘origins of replication,’” said Huilin Li, a biologist at Brookhaven Lab and Stony Brook University, who led the study. “A cell finds those origins in its vast genome with a protein ‘machine’ called the ‘origin recognition complex,’ or ORC.”

In a typical bacterial genome, comprised of several million base pairs — the “letters” of the genetic code — there is only one such origin. However, in more complex eukaryotic organisms, such as humans with a genome of 3.4 billion base pairs, there may be tens of thousands of replication origins so that DNA replication can be carried out simultaneously at these sites to duplicate the genome in a reasonable time.

The goal of the current effort was to understand the first steps of the enormously complex task of duplicating a eukaryotic genome: how the protein machinery ORC recognizes and binds to the origin DNA, and how the origin-bound ORC enables the attachment of additional protein machinery that unwinds the DNA double helix into two single strands in preparation for DNA copying.

“This level of detail on the shape of the origin recognition complex and its interaction with DNA provides insight into a key cellular process, the initiation of DNA replication,” said Daniel Janes, who oversees DNA replication grants at the National Institutes of Health’s National Institute of General Medical Sciences, which partially supported the work. “Because DNA replication is closely tied to cell division, a thorough understanding of the process may lead to new ways to fight the uncontrolled cell division that characterizes cancer.”

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TAGGED: BIOLOGY, GENETICS, SCIENCE



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75 Nobel laureate scientists call for repeal of Louisiana Science Education Act - Zack Kopplin - repealcreationism.com

75 Nobel laureate scientists call for repeal of Louisiana Science Education Act

For Immediate Release

Baton Rouge, LA — (March, 6, 2012) – Senator Karen Carter Peterson (D-New Orleans) has filed Senate Bill 374 to repeal the Louisiana Science Education Act, Louisiana’s misnamed and misguided creationism law.

The repeal effort now has the unprecedented support of 75 Nobel laureate scientists–nearly 40% of all living Nobel laureate scientists in physics, chemistry, or physiology or medicine.  This incredible number surpasses the historic 72 Nobel laureate scientists who filed an amicus brief in opposition to Louisiana’s first creationism law during the Edwards v. Aguillard Supreme Court case.  A complete list of Nobel laureates supporting the repeal effort can be found here.

Nobel laureate chemist and supporter of the repeal effort Sir Harry Kroto says,

“One can only be amazed that [the repeal] has managed to assemble such massive support (75 Nobel laureates) for the effort to ensure that only educational material which is supported by reliable evidence is presented in the science lessons of Louisiana’s schools.”

Earlier this year the conservative Thomas Fordham Institute released a report that said Louisiana’s science standards suffer from a “devastating flaw” because of the Louisiana Science Education Act.

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TAGGED: CREATIONISM, EDUCATION



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Tuesday, March 6, 2012

Church schools shun poorest pupils - Jessica Shepherd and Simon Rogers - The Guardian

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St John's Church of England primary school in Croydon, south London, has 7% of pupils eligible for free meals. The proportion in the borough is 24%. Photograph: Frank Baron for the Guardian

England's faith state schools are failing to mirror their local communities by shunning the poorest pupils in their area, analysis by the Guardian of the latest government figures shows.

The Roman Catholic church, which has repeatedly insisted its schools are inclusive, comes out particularly badly in the examination of data published by the Department for Education (DfE) last month and in December. Three-quarters of Catholic primary and secondary schools have a more affluent mix of pupils than their local area.

The figures also reveal that most Church of England (CofE) primary schools have an intake that is untypically affluent and more middle-class than a year ago. The findings will fuel claims that faith schools have been picking pupils from well-off families by selecting on the basis of religion.

The Guardian analysed the proportion of pupils eligible for free school meals – a key indicator of poverty – in each of England's 19,534 state, non-selective primary and secondary schools. All schools designated for children with special needs were taken out.

The schools have been grouped according to whether they are affiliated to the CofE, the Catholic church or have no religious character. The number of state-funded Muslim and Jewish schools is too small to form a meaningful group – however, the 11 state-funded Muslim schools in England are collectively more reflective of their community, with 67% of primaries and 60% of secondaries having more than the local authority average of free school meal pupils. The 36 Jewish state schools on average have less representation of pupils on free school meals than their local area. There are many Christian schools connected to other denominations, but the data does not specify which denomination.

The proportion of pupils eligible for free school meals in each CofE, Catholic or non-religious school was compared with the proportion of pupils eligible for free school meals in their local authority and among all the comparable schools in the same postcode area.

It is well-known that the average proportion of deprived pupils in faith schools is lower than it is for all schools in England. However, it has not until now been clear whether this is a facet of the areas they serve. Our analysis shows for the first time the extent to which faith and non-faith schools reflect – or fail to reflect – the proportion of poor pupils in their area.

The vast majority of Catholic primary and secondary schools fail to mirror the proportion of poor pupils living in their community, the data reveals. The Catholic church has fought successful battles to retain control of admissions to its schools.

Some 73% of Catholic primaries and 72% of Catholic secondaries have a lower proportion of pupils eligible for free school meals than the average for the local authority.

It is the same for CofE primary and secondary schools. Some 74% of these primaries and 65.5% of secondaries have a smaller proportion of pupils eligible for free school meals than is average for the local authority.

In contrast, non-religious schools tend to reflect their neighbourhoods. Half (51%) of non-religious primaries and 45% of non-religious secondaries have a smaller proportion of pupils eligible for free school meals than is representative for their local authority.

Faith schools fared no better when examined at a more local level. We compared the proportion of poor pupils in each postcode with the proportion of poor pupils in faith schools and non-faith schools studying in that postcode. The data shows 76% of Catholic primaries and 65% of Catholic secondaries have a smaller proportion of pupils eligible for free school meals than is representative of their postcode. This is the case for 63.5% of CofE primaries and 40% of CofE secondaries.

Non-religious primaries and secondaries are far more likely to mirror the proportion of poor pupils in their postcode – just 47% of non-faith primaries and 29% of non-faith secondaries take a smaller proportion of free school meals than is representative for their postcode.

Anna Vignoles, a professor of the economics of education at the Institute of Education, University of London, said the Guardian's findings could be explained by the fact that faith schools draw their pupils from their faith communities, which are not necessarily located in the same postcode or area as their school.

A study by Dr Rebecca Allen and Professor Anne West of the Institute of Education and the London School of Economics, published in 2011, showed that middle class parents are more likely to apply to faith schools – and that the admissions procedures there are easier for them to navigate.

Our data also shows that CofE primary schools are increasingly serving the better-heeled in their communities.

Whereas this year 74% of the church's primaries have a smaller proportion of the poorest pupils than their local authority, the year before 72% did.

At a more local level, the same is the case. This year, 63.5% of the church's primaries have a smaller proportion of the poorest pupils than their postcode, compared to 60% last year.

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TAGGED: FAITH SCHOOLS, SOCIETY



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One Jesus for liberals, another for conservatives - Johnjoe McFadden - Guardian Comment Is Free

The abstract of the original study can be found here.


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Creating God in our own image: a poster shows Jesus in an Argentinian football shirt. Photograph: Arnaldo Pampillon/AP

Love thy neighbour, so long as he is not an illegal immigrant. Blessed are the poor, so long as they are deserving. And, though it may be harder for a rich man to enter the kingdom of heaven than to pass through the eye of a needle, multimillionaires should have no problem passing through the door of the Oval Office.

Religion and politics have always made uneasy bedfellows; yet how can Christians from all shades of the political spectrum reconcile their diverse views with the teachings of a single man?

A study led by Lee Ross of Stanford University in California has found that the Jesus of liberal Christians is very different from the one envisaged by conservatives. The researchers asked respondents to imagine what Jesus would have thought about contemporary issues such as taxation, immigration, same-sex marriage and abortion. Perhaps not surprisingly, Christian Republicans imagined a Jesus who tended to be against wealth redistribution, illegal immigrants, abortion and same-sex marriage; whereas the Jesus of Democrat-voting Christians would have had far more liberal opinions. The Bible may claim that God created man in his own image, but the study suggests man creates God in his own image.

Yet both groups recognised that their own views were not always identical to those of Jesus. The researchers divided issues into those concerned with fellowship (wealth distribution, immigration), and those concerned with morality (gay rights, abortion). Conservatives envisaged a Jesus with views close to their own on morality issues; but they recognised that the man who gave all his possessions to the poor would probably have advocated more progressive taxation policies than those of the Republican party. Conversely, liberals saw Jesus as having similar views as themselves on fellowship issues but they believed his views on gay rights would be to the right of their own.

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TAGGED: POLITICS, RELIGION



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Child welfare report calls for church abuse inquiry - Liz Hobday - ABC News

Thanks to zeerust2000 for the link.


From The World Today, on ABC Radio:

ELEANOR HALL: The report from the Cummins Inquiry into vulnerable children in Victoria has made wide-ranging recommendations to improve the State Government's child protection systems.

But committee also recommended changes to the way that religious organisations deal with abuse, and it says a new investigation is needed to look at that issue.

In Melbourne, Liz Hobday reports.

LIZ HOBDAY: The Cummins report isn't short on advice. After a year looking into child welfare in Victoria it's made more than 90 recommendations.

Among the more controversial is the recommendation that religious ministers should be subject to the mandatory reporting of child abuse.

Here's the Minister for Community Services Mary Wooldridge on ABC Melbourne's Jon Faine program:

MARY WOOLDRIDGE: Well another obviously very controversial and important recommendation...

JON FAINE: It shouldn't be controversial. Why should it be controversial?

MARY WOOLDRIDGE: Well, because any extension to mandatory reporting from a system we've had that's been in place for 15 years has implications but we...

JON FAINE: Given the track record of religious organisations of several denominations surely this one is unarguably needed.

MARY WOOLDRIDGE: Well what we'll be doing is meeting with the religious organisations, meeting with the community - who feel very strongly about it, obviously - and we will have a response in time in relation to that.

LIZ HOBDAY: That track record on abuse issues has made headlines in Victoria again and again.

Last year it emerged that in one region of country Victoria more than 30 people had committed suicide after being abused by priests.

Helen Last from the group In Good Faith and Associates has lobbied the Catholic Church to introduce mandatory reporting.

HELEN LAST: We have talked about the need for clergy to be educated into understanding that victims, criminal matters must be reported to the proper authority, but we have not received any positive response from them in that regard.

LIZ HOBDAY: What do you think of the recommendation for a separate inquiry into religious organisations and the way that they deal with sexual abuse?

HELEN LAST: I think it's absolutely necessary and very, very urgent. We are in touch with so many victims and their families who are suffering terribly because they have either not reported yet to the church or the police because of their lack of faith in those organisations – or they have gone to the church and they have found that process to be totally inappropriate for them and in fact it has caused them more harm.

Listen to this audio report and read full transcript.

TAGGED: ABUSE, VATICAN/ROMAN CATHOLICISM



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Worm-like fossil a 'distant cousin' of humans - The Canadian Press - cbcnews

Thanks to rod-the-farmer for the link.

A tiny worm-like creature that swam the seas half a billion years ago is not exactly the first thing that comes to mind when you think about who you share your genes with.

But according to a newly released analysis of a fossil unearthed in the Canadian Rockies a century ago, the finger-sized creature — known as Pikaia gracilens — is the oldest known member of the chordates — a group containing all animals with a backbone, including humans.

"It's a very, very distant cousin," Jean-Bernard Caron, an assistant professor of ecology and evolutionary biology at the University of Toronto and the study's co-author, said in an interview. "We share the same genes...we share some of the basic features."

However, the chance that humans might have evolved from the five-centemetre-long creature is a "long shot," cautioned Caron.

The research, published Monday in the British scientific journal Biological Reviews, determined Pikaia has a notochord, a flexible rod found in the embryos of all chordates that makes up part of the backbone in vertebrates
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TAGGED: EVOLUTION



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